Seik-Soon Khor Selected Research

Stevens-Johnson Syndrome (Lyell's Syndrome)

11/2019

Identification of HLA-A*02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing.

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Seik-Soon Khor Research Topics

Disease

9	Narcolepsy 01/2023 - 01/2013
4	Cataplexy 12/2018 - 01/2013
3	Hepatitis B 03/2023 - 01/2018
3	COVID-19 01/2023 - 01/2021
3	Disorders of Excessive Somnolence (Hypersomnia) 12/2018 - 01/2013
2	Infections 01/2023 - 01/2020
2	Crohn Disease (Crohn's Disease) 01/2023 - 11/2018
2	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 01/2018
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2018 - 01/2016
2	Panic Disorder (Panic Attack) 01/2016 - 05/2015
2	Sleep Wake Disorders 02/2015 - 01/2013
1	Carcinogenesis 03/2023
1	Liver Neoplasms (Liver Cancer) 03/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Ulcerative Colitis 01/2023
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2023
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023
1	Autoimmune Hepatitis 01/2023
1	Brain Diseases (Brain Disorder) 01/2022
1	Neoplasms (Cancer) 01/2022
1	Seizures (Absence Seizure) 01/2022
1	Viremia 01/2022
1	Retinitis 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 01/2021
1	Non-alcoholic Fatty Liver Disease 08/2020
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 11/2019
1	Disease Susceptibility (Diathesis) 11/2019
1	Hashimoto Disease (Thyroiditis, Hashimoto) 01/2019
1	Graves Disease (Basedow Disease) 01/2019
1	Thyroid Diseases (Thyroid Disease) 01/2019
1	Moyamoya Disease (Moya-Moya Disease) 01/2019
1	Hypersensitivity (Allergy) 01/2018
1	Disease Progression 01/2018
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2018
1	Idiopathic Hypersomnia 01/2015

Drug/Important Bio-Agent (IBA)

9	HLA Antigens (Human Leukocyte Antigens)IBA 03/2023 - 02/2015
7	HLA-DQB1 antigen (HLA DQB1)IBA 01/2022 - 01/2013
6	HLA-DRB1 Chains (HLA DRB1)IBA 01/2023 - 05/2015
3	HLA-A Antigens (HLA-A)IBA 03/2023 - 01/2018
3	VaccinesIBA 01/2023 - 01/2018
3	HLA-DR Antigens (HLA-DR)IBA 01/2023 - 01/2018
2	HLA-DPB1 antigen (HLA DPB1)IBA 01/2023 - 01/2022
2	OrexinsIBA 01/2023 - 05/2014
2	HLA-DRB1*04 antigenIBA 01/2019 - 01/2018
1	HLA-DQA1 antigen (HLA DQA1)IBA 01/2023
1	tofacitinibIBA 01/2023
1	2-mercaptopurineIBA 01/2023
1	vedolizumabIBA 01/2023
1	Ustekinumab (CNTO 1275)FDA Link 01/2023
1	COVID-19 VaccinesIBA 01/2023
1	BNT162 VaccineIBA 01/2023
1	2019-nCoV Vaccine mRNA-1273IBA 01/2023
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 01/2023
1	SteroidsIBA 01/2023
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023
1	Mesalamine (Mesalazine)FDA LinkGeneric 01/2023
1	HLA-A24 AntigenIBA 01/2023
1	Immunoglobulin G (IgG)IBA 04/2022
1	Protein Sorting Signals (Signal Peptide)IBA 01/2022
1	HLA-C Antigens (HLA-C)IBA 01/2021
1	HLA-B*52:01 antigenIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	HLA-DQ Antigens (HLA-DQ)IBA 08/2020
1	MicroRNAs (MicroRNA)IBA 08/2020
1	HLA-DR beta-ChainsIBA 08/2020
1	myosin light chain 2IBA 08/2020
1	HLA-B Antigens (HLA-B)IBA 08/2020
1	Glycoproteins (Glycoprotein)IBA 08/2020
1	Surface Antigens (Surface Antigen)IBA 01/2020
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2020
1	HLA-A*02:06:01 antigenIBA 11/2019
1	Amino Acids FDA Link 11/2018
1	AntibodiesIBA 01/2018
1	HLA-DQA2 antigenIBA 01/2018
1	EpitopesIBA 01/2018
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 10/2016
1	GTP-Binding Proteins (G-Protein)IBA 10/2016
1	Purinergic Receptors (Receptors, Purine)IBA 10/2016
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 10/2016
1	CC ChemokinesIBA 10/2015
1	NeuropeptidesIBA 05/2014

Therapy/Procedure

1	Therapeutics 01/2022
1	Immunotherapy 01/2022